Nitroglycerin may cause flushing of the face, dizziness, tachycardia, and throbbing headache. Large doses cause vomiting, restlessness, blurred vision, hypotension (which can be severe), syncope and rarely cyanosis, and methaemoglobinaemia: impairment of respiration and bradycardia may ensue. Sublingual or buccal Nitroglycerin tablets usually produce a localized burning sensation.